SpamFactor
SpamFactor is a hosted filter for incoming mail from a Dutch company, run on servers in the EU. You pay €9.99 per domain per year, whatever the number of addresses or messages. The dashboard shows why every message was delivered or refused, and reports by email let you release blocked mail with one click. There is an API, and apps for iPhone and Android are coming soon.
Choose SpamFactor when you want good spam filtering for one or more domains at a fixed, low price, with your mail filtered in the EU and every decision visible, and you don't need outbound filtering or archiving.
SpamHero
SpamHero is a hosted filter from iSparks in the United States, priced per domain with unlimited addresses, like SpamFactor. The plans differ in message limits, quarantine and archive days, and the Standard plan adds outbound filtering. There is an API.
Choose SpamHero when you also want to filter outgoing mail, and you are fine with a monthly message limit and a price in US dollars.
MX Guarddog
MX Guarddog is a hosted filter for incoming mail, priced per address. It sends quarantine reports to every user and keeps mail for up to a week when your own server is down. Its website does not say where the servers are, and mentions no API or app.
Choose MX Guarddog when you have a domain with only a few addresses, so a price per address works out cheaper.
SpamExperts
SpamExperts, now part of N-able, filters incoming and outgoing mail and archives it. It is made for web hosting companies, with add-ons for cPanel, Plesk, DirectAdmin and WHMCS, so you usually get it through your hosting provider. Its mobile quarantine app was discontinued in 2022.
Choose SpamExperts when your hosting provider already offers it with your hosting package, or you are a hosting company that wants a filter built into cPanel or Plesk.
N-able Mail Assure
Mail Assure is the sister product of SpamExperts at N-able, made for managed service providers. Besides inbound and outbound filtering it offers long-term archiving, email continuity during an outage and an API.
Choose N-able Mail Assure when you are an MSP that wants one console for archiving, continuity and filtering for many customers, and you buy through a partner.
Hornetsecurity
Hornetsecurity is a German email security company with its own data centres in Germany. Its spam filter is part of a larger range that includes archiving, backup and security for Microsoft 365, sold through IT partners. Its control panel has an API.
Choose Hornetsecurity when you want a large suite from one vendor, beyond spam filtering, and you have an IT partner that sells and manages it.